"Targeted therapy approaches for sarcomas driven by loss of NF1", by Christine Pratilas, MD

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Targeted therapy approaches for sarcomas driven by loss of NF1

Christine Pratilas, MD

Associate Professor

Department of Oncology

Johns Hopkins University

Objectives:

Upon completion of the activity, participants should be better able to:

1. Define the spectrum of NF1-associated nerve sheath tumors and current treatment approaches;

2. Describe key signaling pathways that are activated in NF1-MPNST and potential drugs to target them;

3. Recognize the importance of adaptive signaling changes and acquired resistance in the design of rational combination strategies

*For more information about the University of Minnesota’s Pediatric Grand Rounds, click here: https://med.umn.edu/pediatrics/pediatric-grand-rounds